2021

Original article

• 1.Genotype and Long-term Clinical Course of Bietti Crystalline Dystrophy in Korean and Japanese Patients　Murakami Y, Koyanagi Y, Fukushima M, Yoshimura M, Fujiwara K, Akiyama M, Momozawa Y, Ueno S, Terasaki H, Oishi A, Miyata M, Ikeda H, Tsujikawa A, Mizobuchi K, Hayashi T, Fujinami K, Tsunoda K, Park JY, Han J, Kim M, Lee CS, Kim SJ, Park TK, Joo K, Woo SJ, Ikeda Y, Sonoda KH; Ophthalmol Retina. 5(12):1269-1279, 2021/12/01
• 2.The power of genetic diversity in genome-wide association studies of lipids.　Graham SE, Clarke SL, Wu KHH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Akiyama M, et al.; Nature. 600(7890):675-679, 2021/12/01
• 3.Mapping the genetic architecture of suicide attempt and suicide death using polygenic risk scores for clinically-related psychiatric disorders and traits　Ikuo O, Galfalvy H, Guo J, Akiyama M, Rujescu D, Turecki G, Hishimoto A, Mann JJ; Psychol. Med. 52(11):1-9, 2021/11/18
• 4.Regional and sex differences in retinal detachment surgery: Japan-retinal detachment registry report　Funatsu R, Terasaki H, Sakamoto T, & the Japan Retinal Detachment Registry study group; Sci Rep. 11(1):20611, 2021/10/18
• 5.Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration　Wada I, Nakao S, Yamaguchi M, Kaizu Y, Arima M, Shinichiro Sawa, Sonoda KH; Invest Ophthalmol Vis Sci. 62(13):17, 2021/10/04
• 6.Risk factors for myopia at 1-year corrected age following laser photocoagulation for retinopathy of prematurity　Mori Y, Arima M, Ueda E, Fujiwara K, Seki E, Nakama T, Tsukamoto S, Akiyama M, Sonoda KH; Eye. 35(10):2820-2825, 2021/10/01
• 7.A cross-population atlas of genetic associations for 220 human phenotypes　Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, Narita A, Konuma T, Yamamoto K, Akiyama M, et al.; Nat Genet. 53(10):1415-1424, 2021/09/30
• 8.Alveolar soft part sarcoma of the orbit: A case report　Oda T, Kikuchi K, Togao O, Baba S, Mizoguchi M, Tanabe M, Itoiu M, Yamamoto H, Ishigami K, Hiwatashi A; Radiology Case reports. 16:3766-3771, 2021/09/05
• 9.A case of cat scratch disease diagnosed by Indirect fluorescent antibody assay of igm specific for a Japanese strain of Bartonella henselae.　Uchi SH, Yanai R, Tsuneoka H, Otsuyama KI, Sonoda KH, Kimura K; Retin Cases Brief Rep. 15(5):571-574, 2021/09/01
• 10.Prevalence and incidence rates and treatment patterns of non-infectious uveitis in Japan: real-world data using a claims database　Umazume A, Ohguro N, Okada A A, Namba K, Sonoda KH, Tsuruga H, Morita K, Goto H; Jpn J Ophthalmol. 65(5):657-665, 2021/09/01
• 11.Complete congenital stationary night blindness associated with a novel NYX variant (p.Asn216Lys) in middle-aged and older adult patients　Hayashi T, Murakami Y, Mizobuchi K, Koyanagi Y, Sonoda KH, Nakano T; Ophthalmic Genet. 42(4):412-419, 2021/08/01
• 12.Drainage retinotomy confers risk of epiretinal membrane formation following vitrectomy for rhegmatogenous retinal detachment repair　Ishikawa K, Akiyama M, Mori K, Nakama T, Notomi S, Nakao S, Kohno RI, Takeda A, Sonoda KH; Am J Ophthalmol. 234:20-27, 2021/07/30
• 13.Drusen and pigment abnormality predict the development of neovascular age-related macular degeneration in Japanese patients.　Notomi S, Shiose S, Ishikawa K, Fukuda Y, Kano K, Mori K, Wada I, Kaizu Y, Matsumoto H, Akiyama M, Sonoda KH; PLoS One. 16(7):e0255213, 2021/07/27
• 14.Study protocol for a multi-center, open-label, single-arm phase I/II trial to evaluate the safety and efficacy of ripasudil 0.4% eye drops for retinopathy of prematurity　Arima M, Inoue H, Nakao S, Misumi A, Suzuki M, Matsushita I, Araki S, Yamashiro C, Takahashi M, Ochiai M, Yoshida N, Hirose M, Kishimoto J, Todaka K, Hasegawa S, Kimura K, Kusuhara K, Kondo H, Ohga S, Sonoda KH; BMJ Open 11(7):e047003, 2021/07/27
• 15.A case of primary orbital solitary fibrous tumor with lung metastases 41 years after initial treatment　Tanabe M, Yoshikawa H, Yamada Y, Oda Y, Sonoda KH; Orbit. 10:1-5, 2021/07/14
• 16.Clinical features of RBC-coated IOL after breakthrough vitreous hemorrhage secondary to neovascular age-related macular degeneration　Kim HM, Murakami Y, Woo SJ; J Cataract Refract Surg. 47(7):892-897, 2021/07/01
• 17.Distinguishing Features of Anterior Uveitis Caused by Herpes Simplex Virus, Varicella-Zoster Virus and Cytomegalovirus. 　Terada Y, Kaburaki T, Takase H, Goto H, Nakano S, Inoue Y, Maruyama K, Miyata K, Namba K, Sonoda KH, Kaneko Y, Numaga J, Fukushima M, Horiguchi N, Ide M, Ehara F, Miyazaki D, Hasegawa E, Mochizuki M; Am J Ophthalmol. 227:191-200, 2021/07/01
• 18.Surgical outcomes of cataract surgery for contrast sensitivity and visual acuity in uveitis-associated cataract　Takeda A, Hasegawa E, Notomi S, Ishikawa K, Arima M, Murakami Y, Nakao S, Hisatomi T, Sonoda KH; Clin Ophthalmol. 15:2665-2673, 2021/06/24
• 19.Revesz syndrome with bilateral retinal detachments successfully treated by pars plana vitrectomy.　Asano M, Sonoda KH, Tsukamoto S, Kondo H; Am J Ophthalmol Case Rep. 23:101137, 2021/06/16
• 20.Cohort Profile: the Ganka-Ekigaku Network (GEN), a network of Japanese ophthalmological epidemiology studies　Sasaki M, Miyake M, Fujiwara K, Namba H, Akiyama M, Yanagi Y, Harada S, Tabara Y, Yasuda M, Yamashita H, Kayama T, Tsubota K, Matsuda F, Hashimoto S, Ueda E, Ninomiya T, Takebayashi T, Tsujikawa A, Sonoda KH, Kawasaki R; Ophthalmic Epidemiol. 28(3):237-243, 2021/06/01
• 21.Regional differences in genes and variants causing retinitis pigmentosa in Japan.　Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Komori S, Gao D, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH; Jpn J Ophthalmol. 65(3):338-343, 2021/05/01
• 22.Molecular Signatures of Natural Killer Cells in CMV-Associated Anterior Uveitis, A New Type of CMV-Induced Disease in Immunocompetent Individuals. 　Yawata N, Shirane M, Woon K, Lim X, Tanaka H, Kawano YI, Yawata M, Chee SP, Siak J, Sonoda KH; Int J Mol Sci. 22(7):3623, 2021/03/31
• 23.Disinfectant potential in inactivation of epidemic keratoconjunctivitis-related adenoviruses by potassium peroxymonosulfate.　Hashizume M, Aoki K, Ohno S, Kitaichi N, Yawata N, Gonzalez G, Nonaka H, Sato S, Takaoka A; Eur J Ophthalmol. 31(2):379-384, 2021/03/01
• 24.Epidemiology of uveitis in Japan: a 2016 retrospective nationwide survey　Sonoda KH, Hasegawa E, Namba K, Okada A, Ohguro N, Goto H; Jpn J Ophthalmol. 65:184-190, 2021/03/01
• 25.Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries　Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segre AV, Rouhana JM, Hamel AR, Igo RP, Choquet H, Qassim A, Josyula NS, Bailey JNC, Bonnemaijer P, Iglesias A, Siggs OM, Young TL, Vitart V, Thiadens AAHJ, Karjalainen J, Uebe S, Melles RB, Nair KS, Luben R, Simcoe M, Amersinghe N, Cree AJ, Hohn R, Poplawski A, Chen LJ, Rong SS, Aung T, Vithana E, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23andMe Research Team, Tamiya G, Shiga Y, Yamamoto M, Nakazawa T, ..., Akiyama M, et al.; Nat Commun. 12:1258, 2021/02/24
• 26.Diabetic vascular hyperpermeability: optical coherence tomography angiography and functional loss assessments of relationships among retinal vasculature changes　Arima M, Nakao S, Kaizu Y, Wada I, Yamaguchi M, Fujiwara K, Akiyama M, Stitt AW, Sonoda KH; Sci Rep. 11(1):4185, 2021/02/18
• 27.Eye Explorer: A robotic endoscope holder for eye surgery　Dongbo Zhou, Kimura S, Takeyma H, Haraguchi D, Kaizu Y, Nakao S, Sonoda KH, Tadano K; Int J Med Robot 17(1):1-13, 2021/02/01
• 28.A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa　Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda KH, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T; Commun Biol. 4(1):140, 2021/01/29
• 29.Correlation between Improvement in Visual Acuity and QOL after Ranibizumab Treatment for Age-Related Macular Degeneration Patients: QUATRO study　Oshima Y, Ishibashi Y, Umeda N, Nagata T, Yoshida S, Uchio Eiichi, Kondo H, Sonoda KH, Ishibashi T; BMC Ophthalmol. 21:58, 2021/01/23

Review article

• 1.Drusen and pigmentary abnormality: Two ways leading to AMD progression　Notomi S; J Clin Ophthalmol 5(6):482-485, 2021/11/25
• 2.Vitamin A deficiency-associated corneal perforation in a boy with autism spectrum disorder: A case report and review of the literature　Adachi S, Torio M, Okuzono S, Motomura Y, Ichimiya Y, Sonoda Y, Nagata J, Okamoto M, Notomi S, Snefuji M, Sakai Y, Ohga S; Nutrition 90:111275, 2021/10/01
• 3.Translational research in retinopathy of prematurity: From bedside to bench and back again　Arima M, Fujii Y, Sonoda KH; J Clin Med. 10(2):331, 2021/01/18
• 4.Multi-omics study for interpretation of genome-wide association study　Akiyama M; J Hum Genet. 66(1):3-10, 2021/01/01

Oral & Poster presentation

• 1.A case report of ROSAH Syndrome, a juvenile onset ocular multisystem autosomal dominant disorder　Ito T, Yawata N, Yamana S, Sonoda M, Ishimura M, Eguchi K, Shirane M, Hayashida A, Hasegawa E, Takeda A, Takada H, Ohga S, Sonoda KH; International Ocular Inflammation Society, Thessaloniki, Greece, 2021/12/03
• 2.Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma 　Takeda A, Sonoda KH; International Ocular Inflammation Society, Thessaloniki, Greece, 2021/12/02
• 3.Age-related morphologic abnormalities of retinal pigment epithelium in Tnfrsf10 knockout mice　Mori K, Ishikawa K, Wada I, Kubo Y, Nakama T, Akiyama M, Arima M, Murakami Y, Nakao S, Yoshida S, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 4.Cytomegalovirus protein UL40 leader peptides in ocular fluids of Japanese Cytomegalovirus-associated uveitis　Shirane M, Yawata N, Yamana S, Hayashida A, Ito T, Kaburaki T, Shibata K, Hasegawa E, Takeda A, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 5.Detecting sebaceous carcinoma in whole-histopathological slide images using deep learning. 　Funatsu H, Akiyama M, Tanabe M, Yoshikawa H, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 6.Development of robotic endoscope holder for vitreoretinal surgery 　Sonoda KH, Nakao S, Tadano K; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 7.Effects of Liposome-encapsulated Ripasudil on Proliferative Vitreoretinopathy　Rui ji, Ishikawa K, Mori K, Matsunaga N, Wada I, Nakama T, Nakao S, Ohdo S, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 8.Genetic and Clinical features of RHO-related Retinitis Pigmentosa in Japanese patients　Tsutsui S, Murakami Y, Koyanagi Y, Akiyama M, Ikeda Y, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 9.Recurrence Rate of Cystoid Macular Edema with Topical Dorzolamide Treatment and its Risk Factors in Retinitis Pigmentosa　Shimokawa S, Murakami Y, Fujiwara K, Funatsu J, Nakatake S, Koyanagi Y, Akiyama M, Yoshida S, Takeda A, Ikeda Y, Sonoda KH; The 14 th Joint Meeting of Japan-Chhina-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 10.Trends in the prevalence of diabetic retinopathy: the Hisayama Study　Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Nakamura S, Sonoda KH; The 14th Joint Meeting of Japan-China-Korea Ophthalmologists, Fukuoka,Japan, 2021/11/27
• 11.Impact of Anti-VEGF Therapy on Photoreceptor in Patients with Exudative Age-Related Macular Degeneration　Nakao S; 8th Beijing-Yougnam-Kyushu Retina Meeting, Fukuoka,Japan, 2021/11/26
• 12.Downregulation of TNFRSF10A promotes RPE cell death via PKC deactivation　Mori K, Ishikawa K, Wada I, Kubo Y, Nakama T, Akiyama M, Arima M, Notomi S, Murakami Y, Hisatomi T, Nakao S, Yoshida S, Sonoda KH; ARVO, San Francisco, USA, 2021/05/07
• 13.Polymorphisms of cytomegalovirus UL40 protein signal peptide in Cytomegalovirus-Associated Uveitis　Shirane M, Yamana S, Hayashida A, Yawata N, Takeda A, Sonoda KH; ARVO, San Francisco, USA, 2021/05/06
• 14.Recurrence Rate of Cystoid Macular Edema with Topical Dorzolamide Treeatment and Risk Factors in Retinitis Pigmentosa　Shimokawa S, Murakami Y, Fujiwara K, Funatsu J, Nakatake S, Koyanagi Y, Akiyama M, Yoshida N, Takeda A, Ikeda Y, Sonoda KH; ARVO, San Francisco, USA, 2021/05/06
• 15.Effects of Liposome-encapsulated Ripasudil on Proliferative Vitreoretinopathy　Rui ji, Ishikawa K, Mori K, Matsunaga N, Wada I, Nakama T, Nakao S, Ohdo S, Sonoda KH; ARVO, San Francisco,USA, 2021/05/05
• 16.The role of oxidative DNA damage and response in NMDA-induced retinal ganglion cell death　Okita A, Murakami Y, Shimokawa S, Ikeda Y, Nakabeppu Y, Sonoda KH; ARVO, San Francisco,USA, 2021/05/05
• 17.Morphological evaluation of white spots in the granulomatous uveitis using ultra widefield OCT　Hayashida A, Hasegawa E, Yamana S, Shirane M, Ito T, Takeda A, Yawata N, Sonoda KH; ARVO, San Francisco,USA, 2021/05/03
• 18.Genotype and long-term clinical features of RHO-associated retinitis pigmentosa in Japanese patients　Tsutsui S, Murakami Y, Koyanagi Y, Akiyama M, Ikeda Y, Sonoda KH; ARVO, San Francisco, USA, 2021/05/02
• 19.Effects of Liposome-encapsulated Ripasudil on Proliferative Vitreoretinopathy　Rui ji, Ishikawa K, Mori K, Matsunaga N, Wada I, Nakama T, Nakao S, Ohdo S, Sonoda KH; Annual Meeting of the Japanese Ophthalmological Society, Osaka,Japan, 2021/04/08
• 20.Polymorphisms of Cytomegalovirus UL40 protein signal peptides in Cytomegalovirus-associated uveitis　Shirane M, Yawata N, Yamana S, Hayashida A, Kaburaki T, Shibata K, Ito T, Hasegawa E, Takeda A, Sonoda KH; Annual Meeting of the Japanese Ophthalmological Society, Osaka,Japan, 2021/04/08
• 21.Trends in the prevalence of diabetic retinopathy: the Hisayama Study.　Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Nakamura S, Sonoda KH; The 125the Annual Meeting of the Japanese Ophthalmological Society, Tokyo,Japan, 2021/04/08

Special · Invitation · Education lecture etc.

• 1.Single-cell Multiomics - Is it Applicable to Glaucoma?　Akiyama M; Twenty-seventh Annual Glaucoma Foundation Optic Nerve Rescue and Restoration Think Tank NY, USA, 2021/10/15
• 2.Drainage retinotomy confers risk of epiretinal membrane formation following vitrectomy for rhegmatogenous retinal detachment repair　Ishikawa K; The Asia Retina Congress Young Ophthalmologists session II Seoul Korea, 2021/09/04

Symposium · Instruction · Workshop · Luncheon seminar etc.

• 1.Distinct profiles of inflammatory mediators in the vitreous humor of patients with vitreoretinal lymphoma and endogenous uveitis　Takeda A; International Ocular Inflammation Society Symposium by Japanese Ocular Inflammation Society Analysis of intraocular specimens/tissues: data collection to create virus retinitis and ocular lymphoma, Athens, Greece, 2021/12/05
• 2.Innate immune response in retinal homeostasis and inflammatory disorders　Sonoda KH; TOS 62 Annual Meeting Uveitis Symposium taiwan, 2021/12/04
• 3.From Micro-imaging to Wide-field-imaging in OCT Angiography　Nakao S; Japan-Korea-China Ophthalmologist meeting Fukuoka,Japan, 2021/11/27
• 4.Comprehensive analysis in ocular samples from uveitis　Sonoda KH; 2021 KOS Meeting On the Cutting-Edge of Uveitis Korea(WEB), 2021/10/31
• 5.Glucose tolerance levels and retinal nerve fiber layer thickness: the Hisayama Study　Fujiwara K; Annual Meeting of the Japanese Ophthalmological Society Symposium The International Crosstalk Symposium by Young Ophthalmologists, Osaka,Japan, 2021/04/10

Others

• 1.Association of drainage retinotomy with macular pucker following retinal detachment repair　Ishikawa K; The 8th Beijing- Youngnam- Kyushu Retina Meeting Beijing China（Web), 2021/11/26
• 2.Retinal Imaging: Current Status and Future Direction　Nakao S; China-Japan fundus salon Fukuoka, 2021/08/01
• 3.Vitrectomy with peripapillary internal limiting membrane peeling for macular retinoschisis associated with normal-tension glaucoma　Ishikawa K; Hanlin Garden　 China, 2021/08/01